Presentations

Presentations

View materials from past presentations below

Next-generation Long-acting Implantables using Surface-eroding Elastomers Show: 2019 Controlled Release Society Annual Meeting & Exposition
Date: 07/23/2019 (Presenter: Stephanie Reed, PhD, Technical Manager, New Product Development, Secant Group)

Poly(glycerol sebacate) (PGS) (Regenerez®, Secant Group) is a synthetic polyol resin that can be crosslinked using urethane chemistry to create poly(glycerol sebacate) urethane (PGSU). PGSU is elastomeric, water impermeable, shelf-life stable, biocompatible, and biodegradable via surface erosion. PGSU ultimately offers many advantages over other polymers for long-acting implantables (LAIs), particularly for high-loading, long-duration implants that are gaining interest in the pharmaceutical industry. Download
Next-generation Long-acting Implantables using Surface-eroding Elastomers
Histological and Biomechanical Evaluation of Braided Tissue Engineered Arterial Grafts in a Mouse Model Show: International Symposium for Applied Cardiovascular Biology and Vascular Tissue Engineering
Date: 06/19/2019 (Presenter: Nationwide Children's Hospital)

Tissue-engineered arterial grafts (TEAGs) are designed from biodegradable materials capable of forming a neoartery of autologous tissue that can grow and remodel within the body. Textile braiding techniques have the potential to aid in the creation of compliant TEAGs with tunable mechanical properties. In this work, TEAGs were fabricated from braided polyglycolic acid fibers with or without poly(glycerol sebacate) coating. Download
Histological and Biomechanical Evaluation of Braided Tissue Engineered Arterial Grafts in a Mouse Model